Back to search

Article

Phenyl Propanoid 1’s-1′-Acetoxychavicol Acetate Protects Against Testosterone-Induced Alopecia by Inhibiting Nadph Oxidase

2025-04-22

Abstract excerpt

Androgenetic alopecia is induced by testosterone-mediated anagen-to-catagen transition and matrix keratinocyte apoptosis in hair follicle cells. Activation of Nox isozymes is involved in testosterone-mediated keratinocyte apoptosis, leading to androgenetic alopecia. This indicates that Nox isozymes can serve as therapeutic targets for androgenic alopecia. We screened 38 compounds to evaluate their ROS-inhibition e...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
aa26656b-fd04-5af5-9481-eb7cdbcd0d98
DOI
10.20944/preprints202504.1892.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Phenyl Propanoid 1’s-1′-Acetoxychavicol Acetate Protects Against Testosterone-Induced Alopecia by Inhibiting Nadph OxidaseDOI 10.20944/preprints202504.1892.v1
Identifying the active components and mechanisms of Persicae Semen in treating androgenetic alopecia: Insights from network pharmacology and experimental evaluationsSemantic proximity
Therapeutic Effect of <i>Nepenthes kampotiana</i> Lecomte Ethanol Extract (Nk-EE) on Androgenic Alopecia through the Inhibition of Apoptosis and 5a-Reductase ActivitySemantic proximity
Bioactives in Chinese Proprietary Medicine Modulates 5α-Reductase Activity and Gene Expression Associated with Androgenetic AlopeciaSemantic proximity
Network pharmacological study of ethyl acetate fraction of Ophioglossum vulgatum Linn. in alopecia treatmentSemantic proximity
An analysis of gene expression data involving examination of signaling pathways activation reveals new insights into the mechanism of action of minoxidil topical foam in men with androgenetic alopeciaSemantic proximity
Evaluation of the Expression of Genes Associated with Inflammation and Apoptosis in Androgenetic Alopecia by Targeted RNA-SeqSemantic proximity
The physiological and pharmacological roles of prostaglandins in hair growthSemantic proximity
The role of lipids in promoting hair growth through HIF-1 signaling pathwaySemantic proximity
EXPLORING THE EFFICACY AND THERAPEUTIC POTENTIAL OF MESENCHYMAL STEM CELL–DERIVED EXOSOMES FOR THE TREATMENT OF ANDROGENIC ALOPECIASemantic proximity
The Androgenic Alopecia Protective Effects of Forsythiaside‐A and the Molecular Regulation in a Mouse ModelSemantic proximity
Prevalence of androgenetic alopecia in China: a community-based study in six cities.Semantic proximity
Hair Thickness Growth Effect of Adenosine Complex in Male-/Female-Patterned Hair Loss via Inhibition of Androgen Receptor SignalingSemantic proximity
Select a neighboring publication to make it the new centre.