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Article

Characterization of human gene products homologous to fission yeast multi-drug resistance determinants

2001-01-01

Abstract excerpt

Novel mechanisms involved in the resistance to cytotoxic agents have been recently described both in fission yeast and in mammalian cells. The work described in this thesis was focused on novel determinants of multi-drug resistance in mammalian cells and their possible mechanism of action. Human Pohl, a highly conserved subunit of the regulatory particle of the 26 S proteasome complex, has been shown to confer mod...

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Literature Corpus work
a9bdc8df-62d3-504e-91f5-c87787c26293
DOI
10.21954/ou.ro.0000fce3
Open publication

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