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Topical 5-Fluorouracil and Imiquimod for the Treatment of High-Grade Cervical Intraepithelial Neoplasia: Protocol for a Randomised Open-Label Controlled Trial (TOPFIT-CIN Study)

2025-07-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> There has been a long-standing interest in developing a safe, effective topical therapy for treating high-grade cervical intraepithelial neoplasia (CIN2/3). Combining 5-Fluorouracil (5-FU) and Imiquimod as a topical application may synergistically target CIN lesions while minimising adverse effects associated with excisional procedures. However, more research is...

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Literature Corpus work
a92fb49b-a384-5413-85f4-ccdf32327e15
DOI
10.21203/rs.3.rs-6753716/v1
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Topical 5-Fluorouracil and Imiquimod for the Treatment of High-Grade Cervical Intraepithelial Neoplasia: Protocol for a Randomised Open-Label Controlled Trial (TOPFIT-CIN Study)DOI 10.21203/rs.3.rs-6753716/v1
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