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Elucidating SARS-CoV-2 Neurotropism: A Comprehensive Mendelian Randomization Study on Cerebrospinal Fluid Biomarkers and their Relevance to COVID-19 Neurological Manifestations

2025-04-03

Abstract excerpt

<title>Abstract</title> <p>A mendelian randomization (MR) analysis was conducted to investigate whether SARS-CoV-2 invaded the human nervous system. This was confirmed by an increase in biomarkers found in the cerebrospinal fluid (CSF) and plasma of COVID-19 patients. To confirm the neuroinvasive properties of SARS-CoV-2, a series of analyses were conducted utilizing accessible datasets by MR. In addition, extern...

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Literature Corpus work: a8a06a34-051b-5e7a-82e0-9647a28a6ccc
DOI: 10.21203/rs.3.rs-5574959/v1

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