Article

Harmonizing Clinical Sequencing And Interpretation For The Emerge III Network

2018-11-01

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The eMERGE III Network was tasked with harmonizing genetic testing protocols linking multiple sites and investigators. <h4>Methods</h4> DNA capture panels targeting 109 genes and 1551 variants were constructed by two clinical sequencing centers for analysis of 25,000 participant DNA samples collected at 11 sites where samples were linked to patients with electronic health r...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a757ead3-c75c-59a0-afbc-808ca9f0b8ba
DOI: 10.1101/457523

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Harmonizing Clinical Sequencing And Interpretation For The Emerge III NetworkDOI 10.1101/457523Read

The reckoning: The return of genomic results to 1444 participants across the eMERGE3 NetworkSemantic proximity Read

The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future.Semantic proximity Read

A comprehensive genomic reporting structure for communicating all clinically significant primary and secondary findingsSemantic proximity Read

Concordance between Research Sequencing and Clinical Pharmacogenetic Genotyping in the eMERGE-PGx Study.Semantic proximity Read

Understanding variations in secondary findings reporting practices across U.S. genome sequencing laboratoriesSemantic proximity Read

Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine.Semantic proximity Read

The Clinical Sequencing Evidence-Generating Research Consortium: Integrating Genomic Sequencing in Diverse and Medically Underserved Populations.Semantic proximity Read

Whole genome sequencing as an investigational device for return of hereditary disease risk and pharmacogenomic results as part of the <i>All of Us</i> Research ProgramSemantic proximity Read

Validation of electronic medical record-based phenotyping algorithms: results and lessons learned from the eMERGE network.Semantic proximity Read

Building a Vertically-Integrated Genomic Learning Health System: The Colorado Center for Personalized Medicine BiobankSemantic proximity Read

Reassessment of Genomic Sequence Variation to Harmonize Interpretation for Personalized Medicine.Semantic proximity Read

A Model for Genome-First Care: Returning Secondary Genomic Findings to Participants and Their Healthcare Providers in a Large Research CohortSemantic proximity Read