Back to search

Article

Emergence of carbapenem, beta-lactamase inhibitor and cefoxitin resistant lineages from a background of ESBL-producing <i>Klebsiella pneumoniae</i> and <i>K. quasipneumoniae</i> highlights different evolutionary mechanisms

2018-03-15

Abstract excerpt

Klebsiella pneumoniae is recognised as a major threat to public health, with increasing emergence of multidrug-resistant lineages including strains resistant to all available antibiotics. We present an in-depth analysis of 178 extended-spectrum beta-lactamase (ESBL)-producing Klebsiella strains, with a high background diversity and two dominant lineages, as well as several equally resistant lineages with less pre...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a702199f-a8e0-50d3-a99e-668ae641497b
DOI
10.1101/283291
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Emergence of carbapenem, beta-lactamase inhibitor and cefoxitin resistant lineages from a background of ESBL-producing <i>Klebsiella pneumoniae</i> and <i>K. quasipneumoniae</i> highlights different evolutionary mechanismsDOI 10.1101/283291
<i>Klebsiella pneumoniae</i> as a key trafficker of drug resistance genes from environmental to clinically important bacteriaSemantic proximity
Stepwise evolution of carbapenem-resistance, captured in patient samples and evident in global genomics of <i>Klebsiella pneumoniae</i>Semantic proximity
Genomic dissection of the bacterial population underlying<i>Klebsiella pneumoniae</i>infections in hospital patients: insights into an opportunistic pathogenSemantic proximity
Genomic insights on the potential role of the accessory genome in the emergence of a novel geographically restricted <i>K. pneumoniae</i> lineage as a high-risk cloneSemantic proximity
International and regional spread of carbapenem-resistant <i>Klebsiella pneumoniae</i> in EuropeSemantic proximity
Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health.Semantic proximity
In-depth analysis of <i>Klebsiella aerogenes</i> resistome, virulome and mobilome worldwideSemantic proximity
Global Insights into Evolution and Adaptation in KPC and NDM Coproducing Carbapenem-Resistant <i>Klebsiella pneumoniae</i>Semantic proximity
Clonal background and routes of plasmid transmission underlie antimicrobial resistance features of bloodstream Klebsiella pneumoniaeSemantic proximity
Genomic epidemiology of Klebsiella pneumoniae in Italy and novel insights into the origin and global evolution of its resistance to carbapenem antibiotics.Semantic proximity
Klebsiella pneumoniae in Germany: An overview on spatiotemporal distribution and resistance development in humansSemantic proximity
Integrated chromosomal and plasmid sequence analyses reveal diverse modes of carbapenemase gene spread among Klebsiella pneumoniaeSemantic proximity
Select a neighboring publication to make it the new centre.