Article

The possible links between COPD and lung cancer : cellular and mitochondrial function in airway epithelial cells

2019-01-01

Abstract excerpt

Cigarette smoke (CS) is a major risk factor for both COPD and lung cancer and many lung cancer patients have COPD. CS-derived oxidant exposure in airway epithelial cells leads to abnormal function. Persistent inflammation in COPD together with mutations and dysregulated cell cycle contributes to lung cancer development. Mitochondria are the hub of bioenergetics, reactive oxygen species (ROS) production and intrace...

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Literature Corpus work: a6e8aa94-b05f-5e32-b35f-31eba37c1503
DOI: 10.25560/73909

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