Article

GYY4137 ameliorates sepsis-induced cardiomyopathy via inhibiting NLRP3 Inflammasome activity and reduction of oxidative stress in the myocardium

2022-05-11

Abstract excerpt

BACKGROUND: Sepsis-induced cardiomyopathy often leads to bad prognosis of patients, and even death. However, there is no effective therapeutic strategies for sepsis-caused cardiomyopathy. GYY4137 has positive therapeutic effects in many diseases. The aim of this study was to explore the mechanism underlying the sepsis-induced cardiomyopathy and investigate the protective role of the hydrogen sulfide (H 2 S) donor...

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Literature Corpus work: a6b3efb5-90ea-5d25-b41d-e0d56ea46d1b
DOI: 10.21203/rs.3.rs-1060356/v2

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