Article
Application of Metagenomic Next-Generation Sequencing in The Diagnosis and Treatment Guidance of Pneumocystis Jirovecii Pneumonia in Renal Transplant Recipients
2021-02-22
Abstract excerpt
<h4>Purpose: </h4> Pneumocystis jirovecii pneumonia (PJP) is difficult to be diagnosed, so this study explored if PJP could be diagnosed by metagenomic next-generation sequencing (mNGS) and if mNGS could guide the therapy of PJP. <h4>Methods: </h4>: mNGS successfully diagnosed 13 out of 14 PJP recipients with 11 through peripheral blood samples, verified by PCR. Ten non-PJP recipients were enrolled as the control...
Topics
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- Animal Virus Infections Studies
- Antifungal resistance and susceptibility
- Bacteriophages and microbial interactions
- Cytomegalovirus and herpesvirus research
- Genomics and Phylogenetic Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Pneumonia and Respiratory Infections
- Respiratory viral infections research
Identifiers and source
- Literature Corpus work
- a5efea67-4443-57eb-b709-8ee592869375
- DOI
- 10.21203/rs.3.rs-144092/v2
