Article

COVIDOUTCOME – Estimating COVID Severity Based on Mutation Signatures in the SARS-CoV-2 Genome

2021-04-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Numerous studies demonstrate frequent mutations in the genome of SARS-CoV-2. Our goal was to statistically link mutations to severe disease outcome. <h4>Methods</h4> We used an automated machine learning approach where 1,594 viral genomes with available clinical follow-up data were used as the training set (797 “severe” and 797 “mild”). The best algorithm, based on random...

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Literature Corpus work: a515b276-ca26-51cb-82a1-c6a0cd2fa7f7
DOI: 10.1101/2021.04.01.438063

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