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The role of gut microbiota, immune system, and autophagy in the pathogenesis of inflammatory bowel disease: Molecular mechanisms and therapeutic approaches

2024-10-17

Abstract excerpt

The crosstalk between gut microbiota, intestinal epithelial cells, and innate and adaptive immune system governs the maintenance of the intestinal homeostasis. Any interference in this tight dialogue and in the processes preserving cellular homeostasis (e.g., autophagy) may dysregulate the immune response and impair the clearance of harmful bacteria favoring the dysbiotic alteration of the microbial flora that lea...

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Literature Corpus work
a2923c93-976d-5b1d-908e-e96d3a0a7c48
DOI
10.1016/j.amolm.2024.100056
Open publication

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The role of gut microbiota, immune system, and autophagy in the pathogenesis of inflammatory bowel disease: Molecular mechanisms and therapeutic approachesDOI 10.1016/j.amolm.2024.100056
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