Adjuvant Chemotherapy Versus Radiotherapy Alone in Pediatric Intracranial Ependymoma: A Systematic Review and Meta-analysis

Abstract excerpt

<title>Abstract</title> <p>Background Pediatric intracranial ependymoma remains a therapeutically challenging central nervous system tumor in which long-term outcomes depend primarily on maximal safe resection and postoperative focal radiotherapy (RT). Thus, the survival benefit of adjuvant chemotherapy remains uncertain. However, no meta-analysis has directly pooled survival outcomes comparing adjuvant chemothe...

Topics

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• Biopsy
• Central Nervous System Neoplasms
• Combined Modality Therapy
• Disease Management
• Ependymoma
• Multimodal Imaging
• Neoplasm Grading
• Oncogene Proteins, Fusion

Identifiers and source

Literature Corpus work

a201d8ed-c47d-56df-98c4-555912178ae6

DOI

10.21203/rs.3.rs-10271134/v1