Article

Cutting across structural and transcriptomic scales translates time across the lifespan and resolves frontal cortex development in human evolution

2020-08-07

Abstract excerpt

How the unique capacities of human cognition arose in evolution is a question of enduring interest. It is still unclear which developmental programs are responsible for the emergence of the human brain. The inability to determine corresponding ages between humans and apes has hampered progress in detecting developmental programs leading to the emergence of the human brain. I harness temporal variation in anatomica...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a16ab3d4-d371-5c84-8da1-ea5c52ccb4ee
DOI: 10.1101/2020.08.06.240077

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cutting across structural and transcriptomic scales translates time across the lifespan and resolves frontal cortex development in human evolutionDOI 10.1101/2020.08.06.240077Read

Tracing cortical circuits in humans and non-human primates from high resolution connectomic, transcriptomic, and temporal dimensionsSemantic proximity Read

Transcription, structure, and organoids translate time across the lifespan of humans and great apesSemantic proximity Read

Brain wiring and supragranular-enriched genes linked to protracted human frontal cortex developmentSemantic proximity Read

Isoswitching in human brain development and agingSemantic proximity Read

The trait specific timing of accelerated genomic change in the human lineageSemantic proximity Read

Multidimensional brain-age prediction reveals altered brain developmental trajectory in psychiatric disordersSemantic proximity Read

Mapping the genetic evolutionary timeline of human neural and cognitive traitsSemantic proximity Read

Deciphering developmental gradients in human hippocampusSemantic proximity Read

Regional patterns of human cortex development correlate with underlying neurobiologySemantic proximity Read

Time-varying gene expression network analysis for evolution of human prefrontal cortexSemantic proximity Read

Continuity and discontinuity in human cortical development and change from embryonic stages to old ageSemantic proximity Read

Molecular networks and the evolution of human cognitive specializations.Semantic proximity Read