Article

Evaluating the Role of Cell-free Fetal DNA in Inflammation and Spontaneous Preterm Birth

2017-09-20

Abstract excerpt

Preterm birth is the leading cause of neonatal mortality. While spontaneous preterm birth (sPTB) is the cause of over 70% of PTB, the pathogenesis behind sPTB remains unclear. Cell-free fetal DNA (cff-DNA) originates from the placenta and is increased in women who develop PTB. It has been demonstrated that fetal DNA is hypomethylated and is pro-inflammatory. The pro-inflammatory properties of placental-derived DNA...

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Literature Corpus work: a06f2474-daa4-5fd2-ac11-2ed45281ad08
DOI: 10.1101/191528

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