Article

A Pan-Cancer Analysis of SRD5A1, a Potential New Carcinogenic Indicator Related to Immune Infiltration and Prognosis of UCEC

2022-08-24

Abstract excerpt

<h4>Background: </h4> Steroid 5-Alpha-reductase ty p e I (SRD5A1) converts testosterone to dihydrotestosterone and regulates sex hormone levels, which facilitates tumor incidence or p rogression. However, the molecular mechanism behind SRD5A1's role in p an-cancer remains unknown. <h4>Methods: </h4>: RNA-seq data from TCGA and the Genoty p e-Tissue Ex p ression (GTEx) database were used to examine SRD5A1 ex p ress...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a02a4e74-de93-5acd-b91a-ec2d8573c047
DOI: 10.21203/rs.3.rs-1951445/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Pan-Cancer Analysis of SRD5A1, a Potential New Carcinogenic Indicator Related to Immune Infiltration and Prognosis of UCECDOI 10.21203/rs.3.rs-1951445/v1Read

Pan-Cancer Analysis of Molecular Characteristics and Oncogenic Role of PRMT5 in Human CancersSemantic proximity Read

Identifying the Role of NUDCD1 in Human Tumors from Clinical and Molecular MechanismsSemantic proximity Read

Identifying the Role of NUDCD1 in Human Tumors from Clinical and Molecular Mechanisms: A Study Based On Comprehensive Bioinformatics and Experimental ValidationSemantic proximity Read

Integrated Multi-omics Analyses Identify CDCA5 as a Novel Biomarker Associated with Alternative Splicing, Tumor Microenvironment, and Cell Proliferation in Colon Cancer Via Pan-cancer AnalysisSemantic proximity Read

A Pan-Cancer Analysis Reveals CLEC5A as a Biomarker for Cancer Immunity and PrognosisSemantic proximity Read

IncRNA VIM-AS1 expression is positively correlated with the prognosis and immune infiltration in lung adenocarcinomaSemantic proximity Read

PTGDS is a potential marker for lung adenocarcinoma identified from multi-omics pan-cancer dataSemantic proximity Read

Multi-omics pan-cancer analysis reveals an immunological role and prognostic potential of WDR76Semantic proximity Read

Pan-cancer analysis reveals potential of RRM2 as a prognostic and immunological biomarker in human cancerSemantic proximity Read

Prognosis and Biological Function of CYB5R Family in Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma: A Multi-omics AnalysisSemantic proximity Read

High Expression of SRD5A3 in Human Hepatocellular Carcinoma (HCC) Predicts Poor Prognosis: A Study Based on TCGA DataSemantic proximity Read

A Pan-Cancer Analysis of SLC12A5 Reveals Its Correlations with Tumor Immunity.Semantic proximity Read