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Mining transcriptomics and clinical data reveals ACE2 expression modulators and identifies cardiomyopathy as a risk factor for mortality in COVID-19 patients

2020-10-23

Abstract excerpt

Angiotensin-converting enzyme 2 ( ACE2 ) is the cell-entry receptor for SARS-CoV-2. It plays critical roles in both the transmission and the pathogenesis of the coronavirus disease 2019 (COVID-19). Comprehensive profiling of ACE2 expression patterns will help researchers to reveal risk factors of severe COVID-19 illness. While the expression of ACE2 in healthy human tissues has been well characterized, it is not k...

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Literature Corpus work
9f4096c4-80de-5950-86aa-2ca054f0886e
DOI
10.1101/2020.10.20.20216150
Open publication

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Mining transcriptomics and clinical data reveals ACE2 expression modulators and identifies cardiomyopathy as a risk factor for mortality in COVID-19 patientsDOI 10.1101/2020.10.20.20216150
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