Article

A Biodegradable, Tacrolimus-releasing Nerve Wrap Promotes Peripheral Nerve Regeneration

2021-10-25

Abstract excerpt

Axonal regeneration following nerve repair is slow and often incomplete, resulting in poor functional recovery and sometimes lifelong disability. Yet, there are no FDA-approved therapies available to promote nerve regeneration. Tacrolimus accelerates axonal regeneration, but systemic side-effects presently outweigh its potential benefits for peripheral nerve surgery. We have developed a biodegradable drug delivery...

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Identifiers and source

Literature Corpus work: 9bd105aa-6130-5043-938b-9ea86d9f2d41
DOI: 10.1101/2021.10.23.465561

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