Back to search

Article

Genetic insights on the mechanisms of human cortical folding

2026-03-09

Abstract excerpt

The unique and intricate pattern of human cortical folding is rooted in fetal neurodevelopmental processes and can now be comprehensively quantified by new neuroimaging-derived measures of sulcal complexity. Here, we provide the first genetic maps of human sulcal complexity. Beginning with large effects of rare variants, we survey nine different neurogenetic syndromes ( n =615), detecting visible changes in sulca...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
9bac62c3-de95-5b4e-86f3-78578975f1b3
DOI
10.64898/2026.03.06.709690
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Genetic insights on the mechanisms of human cortical foldingDOI 10.64898/2026.03.06.709690
The genetic architecture of human cortical foldingSemantic proximity
A bimodal taxonomy of adult human brain sulcal morphology related to timing of fetal sulcation and trans-sulcal gene expression gradientsSemantic proximity
A bipolar taxonomy of adult human brain sulcal morphology related to timing of fetal sulcation and trans-sulcal gene expression gradientsSemantic proximity
Genetic map of regional sulcal morphology in the human brainSemantic proximity
Genetic insights into human cortical organization and development through genome-wide analyses of 2,347 neuroimaging phenotypes.Semantic proximity
Genetic Influence on the Sulcal Pits: On the Origin of the First Cortical Folds.Semantic proximity
Self-supervised representations reveal the genetic architecture of human cortical foldingSemantic proximity
The genetics of cortical organisation and development: a study of 2,347 neuroimaging phenotypesSemantic proximity
Mapping the genetic architecture of human cortical expansion and its links to neuropsychiatric disordersSemantic proximity
Neuroimaging genomics as a window into the evolution of human sulcal organizationSemantic proximity
Molecular and Cellular Underpinnings of Spatial Heterogeneity in Fetal Cortical FoldingSemantic proximity
The reliability and heritability of cortical folds and their genetic correlations across hemispheresSemantic proximity
Select a neighboring publication to make it the new centre.