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Descending Brainstem Systems Contribute to Ankle Clonus in Humans with Spinal Cord Injury

2026-05-22

Abstract excerpt

Ankle clonus is a sustained, involuntary, rhythmic muscle contraction frequently observed in humans with spinal cord injury (SCI). Although its pathophysiology remains incompletely understood, converging evidence suggests a role for brainstem systems in its generation. Following SCI, brainstem neuromodulatory inputs partially compensate for the loss of descending motor pathways by regulating motoneuron excitabilit...

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Literature Corpus work
9b98ea72-76ae-535e-957a-7ff7af50390e
DOI
10.64898/2026.05.21.26353256
Open publication

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Descending Brainstem Systems Contribute to Ankle Clonus in Humans with Spinal Cord InjuryDOI 10.64898/2026.05.21.26353256
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