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Predicting Continuous Cognitive Decline: The Generalizability of a Multimodal Machine Learning Approach Including Structural MRI and Non-Brain Data

2026-01-15

Abstract excerpt

Aging is often accompanied by cognitive decline, but the extent, timing, and severity of this process is subject to large inter-individual variability. Predicting cognitive decline along a continuum, encompassing healthy age-related decline, mild cognitive impairment, and dementia, allows for more precise individual-level predictions. Previous work has demonstrated that machine learning (ML) models combining risk...

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Literature Corpus work
9a9ddcf6-de84-5f13-a4e7-4272b3d53678
DOI
10.64898/2026.01.13.26343927
Open publication

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