Article

Is Reversible Cognitive Frailty a Unified Syndrome? Insights from a Bifactor Exploratory Structural Equation Model in People with HIV

2026-01-16

Abstract excerpt

<title>Abstract</title> <p>Reversible cognitive frailty, defined as co-occurring self-reported cognitive difficulty and prefrailty or frailty, may mark an early window for intervention in people with HIV. However, whether this construct reflects a unified syndrome or independent co-occurring processes remains unclear. We tested whether a general reversible cognitive frailty factor underlies shared variance betwee...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9a5cf21d-a44e-576d-ae14-b1743ccc683d
DOI: 10.21203/rs.3.rs-8516156/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Is Reversible Cognitive Frailty a Unified Syndrome? Insights from a Bifactor Exploratory Structural Equation Model in People with HIVDOI 10.21203/rs.3.rs-8516156/v1Read

Prevalence of Frailty Phenotypes in Older People Living with HIV: A Cross-Sectional Study from Brazil.Semantic proximity Read

Cardiometabolic disease among frailty phenotype clusters in adults aging with HIV.Semantic proximity Read

Development, Construct Validity, and Predictive Validity of a Continuous Frailty Scale: Results From 2 Large US Cohorts.Semantic proximity Read

Multisystem frailty phenotypes and associated factors among older adults in Türkiye: A nationally representative study.Semantic proximity Read

Development and Validation of a Multidimensional Physical Pre-Frailty Index for Early Detection of Functional Decline in Community-Dwelling Older AdultsSemantic proximity Read

Association Between Frailty and Components of the Frailty Phenotype With Modifiable Risk Factors and Antiretroviral Therapy.Semantic proximity Read

Screening for intrinsic capacity and frailty in the primary care population with multimorbidity using the Integrated Care for Older People Screening Tool and two different frailty measures – the Frailty Phenotype and Clinical Frailty Scale: a cross-sectional studySemantic proximity Read

Gender-Specific Determinants of Frailty in Aging People with HIV: Evidence for a Multidimensional Vulnerability Phenotype in Women.Semantic proximity Read

Frailty and Emergency Department Visits Among Chinese Middle-Aged and Older Adults: Implications for Nurse-Led Screening and Transitional CareSemantic proximity Read

Multimorbidity Patterns, Frailty, and Survival in Community-Dwelling Older Adults.Semantic proximity Read

Measuring Frailty: A Comparison of the Cumulative Deficit Model of Frailty in Survey and Routine DataSemantic proximity Read

Targeting Cognitive Frailty: Clinical and Neurobiological Roadmap for a Single Complex PhenotypeSemantic proximity Read