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Diagnostic Evidence GAuge of Single cells (DEGAS): A flexible deep-transfer learning framework for prioritizing cells in relation to disease

2020-06-16

Abstract excerpt

We propose DEGAS (Diagnostic Evidence GAuge of Single cells), a novel deep transfer learning framework, to transfer disease information from patients to cells. We call such transferrable information “impressions,” which allow individual cells to be associated with disease attributes like diagnosis, prognosis, and response to therapy. Using simulated data and ten diverse single cell and patient bulk tissue transcr...

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Literature Corpus work
99f112dd-ed42-5dfc-a113-a5dfedbe2234
DOI
10.1101/2020.06.16.142984
Open publication

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Diagnostic Evidence GAuge of Single cells (DEGAS): A flexible deep-transfer learning framework for prioritizing cells in relation to diseaseDOI 10.1101/2020.06.16.142984
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