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General Anesthesia in Psychiatric Patients Undergoing Orthopedic Surgery: A Mechanistic Narrative Review “When the brain is unstable, keep it awake.”

2025-11-18

Abstract excerpt

Orthopedic and lower limb fracture surgeries are among the most frequent emergency procedures and are commonly performed under general anesthesia (GA); Background and clinical significance: Epidemiologically, postoperative coma after GA is rare (0.005–0.08%), but delayed awakening (2–4%) and postoperative delirium or postoperative cognitive dysfunction (POCD) (15–40%) remain significant. These neurological complic...

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Literature Corpus work
99210636-1468-5d7e-b9c0-1b910449c240
DOI
10.20944/preprints202511.1293.v1
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General Anesthesia in Psychiatric Patients Undergoing Orthopedic Surgery: A Mechanistic Narrative Review “When the brain is unstable, keep it awake.”DOI 10.20944/preprints202511.1293.v1
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