Article

Proton Pump Inhibitor Use, CYP2C19 genotypes, and Subsequent Incidence of Chronic Kidney Disease

2025-01-15

Abstract excerpt

<title>Abstract</title> <p>Background The widespread use of proton pump inhibitors (PPIs) has generated concerns about side effects Numerous studies have suggested that PPIs use may increase the risk of kidney disease. In particular, it is unclear whether genotype of the CYP2C19 enzyme system, the main metabolic pathway of PPIs, modifies the association between PPIs and the development of chronic kidney disease...

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Literature Corpus work: 98b71467-925d-5d22-b34f-e4ab8b04a7a0
DOI: 10.21203/rs.3.rs-5788578/v1

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