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Safety and Cross-Reactive Immune Response Against the Omicron Variant of a Third Dose of CoronaVac, and Immune Persistence of Primary Immunization in Healthy Children and Adolescents: Interim Results from a Double-Blind, Randomised, Placebo-Controlled Phase 2 Clinical Trial

2022-05-03

Abstract excerpt

Background: A booster dose of COVID-19 vaccine is required to prolong immune persistence and strengthen the protection against variants. Therefore, we assessed the safety and immunogenicity of homologous boosting with an inactivated vaccine (CoronaVac), as well as the cross-neutralising activity against the Omicron variant in children and adolescents aged 3-17 years.<br><br>Methods: In the phase 2 clinical trial,...

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Literature Corpus work
95beaa08-4d8e-5fe8-92a6-2622312e636d
DOI
10.2139/ssrn.4099431
Open publication

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Safety and Cross-Reactive Immune Response Against the Omicron Variant of a Third Dose of CoronaVac, and Immune Persistence of Primary Immunization in Healthy Children and Adolescents: Interim Results from a Double-Blind, Randomised, Placebo-Controlled Phase 2 Clinical TrialDOI 10.2139/ssrn.4099431
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