Article

Osteonecrosis in Gaucher Disease in the era of multiple therapies: biomarker set for risk stratification from a tertiary referral center

2023-03-27

Abstract excerpt

<h4>BACKGROUND</h4> A salutary effect of treatments for Gaucher disease (GD) has been reduction in the incidence of avascular osteonecrosis (AVN). However, there are reports of AVN in patients receiving enzyme replacement therapy (ERT), and it is not known whether it is related to individual treatments, GBA genotypes, phenotypes, biomarkers of residual disease activity or anti-drug antibodies. <h4>OBJECTIVE</h4...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 946b6980-dc2e-537e-b8bc-6d3032985786
DOI: 10.1101/2023.03.21.23287476

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Osteonecrosis in Gaucher Disease in the era of multiple therapies: biomarker set for risk stratification from a tertiary referral centerDOI 10.1101/2023.03.21.23287476Read

Osteonecrosis in Gaucher disease in the era of multiple therapies: Biomarker set for risk stratification from a tertiary referral centerSemantic proximity Read

In-Depth Phenotyping for Clinical Stratification of Gaucher DiseaseSemantic proximity Read

Clinicogenetic Profile, Treatment Modalities, and Mortality Predictors of Gaucher Disease: A 15-Year Retrospective Study.Semantic proximity Read

Risk factors for fractures and avascular osteonecrosis in type 1 Gaucher disease: a study from the International Collaborative Gaucher Group (ICGG) Gaucher Registry.Semantic proximity Read

Baseline characteristics of 32 patients with Gaucher disease who were treated with imiglucerase: South African data from the International Collaborative Gaucher Group (ICGG) Gaucher Registry.Semantic proximity Read

Recent advances in the diagnosis and management of Gaucher disease.Semantic proximity Read

Skeletal involvement in Gaucher disease: An observational multicenter study of prognostic factors in the Argentine Gaucher disease patients.Semantic proximity Read

The Gaucher registry: demographics and disease characteristics of 1698 patients with Gaucher disease.Semantic proximity Read

Concurrent Genetic Disorders in Gaucher Disease: Insights into Complex Phenotypes, Genetic Modifiers, and Targeted TherapiesSemantic proximity Read

Identification of risk features for complication in Gaucher’s Disease patients: A Machine Learning analysis of the Spanish Registry of Gaucher Disease.Semantic proximity Read

Patient and caregiver burden of neuronopathic Gaucher disease: The GARDIAN Registry experienceSemantic proximity Read

3 Gaucher's disease: clinical features and natural historySemantic proximity Read