Article

Omega-3 polyunsaturated fatty acids affect leptin receptor gene expression in pituitary gh4c1 cell line

2009-08-01

Abstract excerpt

Leptin (Ob) and Ob receptor (Ob-Rb) genes are expressed in human and rodent anterior pituitary, and an autocrine/paracrine loop in the production and regulation of Ob and Ob-Rb in this tissue has been suggested. As brain membranes contain large amounts of polyunsaturated fatty acids (PUFAs), and PUFA may affect the levels of leptin as well as the receptor's environment, a possible regulatory role of exogenous PUFA...

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Literature Corpus work: 93c8d97a-d94e-5e04-960b-194d62e55ee8
DOI: 10.1111/j.1745-4522.2009.01153.x

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