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Proton-Pump Inhibitors Versus H2-Receptor Antagonists on the Risk of Major Osteoporotic Fractures: A Global Propensity-Score-Matched Cohort Study

2025-11-10

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Long-term suppression of gastric acid is crucial for various conditions; however, proton-pump inhibitors (PPIs) may negatively impact skeletal health more than histamine-2 receptor antagonists (H2RAs). There is limited head-to-head data, particularly within Asian communities that have unique calcium consumption and drug metabolism patterns. <bold>Methods</bol...

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Literature Corpus work: 92ce2ba1-2f60-5939-9d33-a45abaa8f78f
DOI: 10.21203/rs.3.rs-7725160/v1

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