Article

Silencing HOXC13 exerts anti-prostate cancer effects by inducing DNA damage and activating cGAS/STING/IRF3 pathway

2023-09-13

Abstract excerpt

<title>Abstract</title> <p>Background Advanced prostate cancer (PCa) will develop into castration-resistant prostate cancer (CRPC) and lead to poor prognosis. As the primary subtype of CRPC, CRPC-AR accounts for the major induction of PCa heterogeneity. CRPC-AR is mainly driven by 25 transcription factors (TFs), which we speculate may be the key factors driving PCa toward CRPC. Therefore, it is necessary to clar...

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Literature Corpus work: 929e3b4f-a488-560d-af90-8c96efafefff
DOI: 10.21203/rs.3.rs-3334923/v1

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