Article

Genetic and clinical phenotypic analysis of familial stapes sclerosis caused by a NOG mutation

2020-12-09

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>The noggin protein encoded by the NOG gene can interfere with the binding of bone morphogenetic protein to its receptor, thus affecting bone and joint development. The symptoms include abnormal skeletal development and conductive deafness.<bold>Methods: </bold>In a<bold> </bold>retrospective study, clinical data of the proband and her family members, including 8...

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Literature Corpus work: 92999eaa-353c-5f27-b240-ffdd29edc669
DOI: 10.21203/rs.3.rs-42135/v4

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