Article

A robust and transformation-free joint model with matching and regularization for metagenomic trajectory and disease onset

2022-04-20

Abstract excerpt

<h4>Background</h4> To identify operational taxonomy units (OTUs) signaling disease onset in an observational study, a powerful strategy was selecting participants by matched sets and profiling temporal metagenomes, followed by trajectory analysis. Existing trajectory analyses modeled individual OTU or microbial community without adjusting for the within-community correlation and matched-set-specific latent facto...

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Literature Corpus work: 910ea749-f2fb-5236-9778-e436e9bdd5e6
DOI: 10.1101/2022.04.19.488854

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