Article
Identification and verification of biomarkers related to senescence-associated secretory phenotype in type 2 diabetes
2025-11-11
Abstract excerpt
<title>Abstract</title> <p>This study aimed to identify senescence-associated secretory phenotype (SASP)-related biomarkers in type 2 diabetes (T2DM) and investigate their biological functions. SASP-related genes (SASP-RGs) were collected from literature, and differentially expressed genes (DEGs) were obtained from datasets GSE15932 and GSE21321. Candidate genes were selected by intersecting DEGs with SASP-RGs, f...
Topics
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- Adipokines, Inflammation, and Metabolic Diseases
- Advanced Glycation End Products research
- Atherosclerosis and Cardiovascular Diseases
- Gestational Diabetes Research and Management
- Inflammasome and immune disorders
- Oral microbiology and periodontitis research
- Single-cell and spatial transcriptomics
- Telomeres, Telomerase, and Senescence
Identifiers and source
- Literature Corpus work
- 8dc07862-6a36-5d6a-8fbc-abce34810af3
- DOI
- 10.21203/rs.3.rs-7839443/v1
