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Understanding the role of SGLT2 inhibitors in glycogen storage disease type Ib: the experience of one UK centre

2022-02-11

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Glycogen storage disease type Ib (GSD Ib) is a severe disorder of carbohydrate metabolism due to bi-allelic variants in <italic>SLC37A4</italic>. It is associated with neutropaenia and neutrophil dysfunction, which has recently been attributed to the accumulation of 1,5-anhydroglucitol-6-phosphate (1,5AG6P) within neutrophils. Treatment with sodium-glucose co-tr...

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Literature Corpus work: 8d94be54-0b07-522a-a7ce-49ec2ea2eb22
DOI: 10.21203/rs.3.rs-1260734/v1

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