Article

Evaluation of large language models for discovery of gene set function

2023-09-18

Abstract excerpt

<title>Abstract</title> <p>Gene set analysis is a mainstay of functional genomics, but it relies on manually curated databases of gene functions that are incomplete and unaware of biological context. Here we evaluate the ability of OpenAI’s GPT-4, a Large Language Model (LLM), to develop hypotheses about common gene functions from its embedded biomedical knowledge. We created a GPT-4 pipeline to label gene sets w...

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Literature Corpus work: 8d459f57-3c5e-5d22-953e-2d5bd80ed589
DOI: 10.21203/rs.3.rs-3270331/v1

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