Discriminating Inflammation from Malignancy with Short-Dynamic Patlak Parametric 18F-FDG PET/CT

Abstract excerpt

<h4>Aim/Introduction</h4> Differentiating malignant from inflammatory uptake on 18 F-FDG PET/CT remains a major diagnostic challenge, as standardized uptake value (SUV) lacks specificity. Dynamic acquisitions with Patlak analysis can separate metabolized from unmetabolized tracer, potentially improving discrimination. We evaluated whether short-duration dynamic FDG PET/CT with Patlak parametric imaging provides c...

Topics

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• Area Under Curve
• Cancer, Hypoxia, and Metabolism
• Contrast Media
• Ki-67 Antigen
• Medical Imaging Techniques and Applications
• Models, Theoretical
• Receptor, ErbB-2
• Receptors, Estrogen

Identifiers and source

Literature Corpus work

8c8c7000-87e0-596e-b182-131fb11e79f0

DOI

10.1101/2025.09.30.25336991