Article

UNICORN: Towards Universal Cellular Expression Prediction with a Multi-Task Learning Framework

2025-01-25

Abstract excerpt

Sequence-to-function analysis is a challenging task in human genetics, especially in predicting cell-type-specific multi-omic phenotypes from biological sequences such as individualized gene expression. Here, we present UNICORN, a new method with improved prediction performances than the existing methods. UNICORN takes the embeddings from biological sequences as well as external knowledge from pre-trained foundati...

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Literature Corpus work: 8c82d56c-9977-5caf-b7a5-135762c20f2c
DOI: 10.1101/2025.01.22.634371

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