Article

Preoperative Prediction of Residual Cancer Burden After Neoadjuvant Chemotherapy in Breast Cancer: A Multimodal Machine Learning Approach and Implications for Clinical Decision Support

2026-08-18

Abstract excerpt

<h4>Background</h4> Residual cancer burden (RCB) after neoadjuvant chemotherapy (NAC) offers finer prognostic stratification than binary pathologic complete response, and increasingly guides adjuvant treatment intensity. Predicting four-tier RCB class from preoperative data could inform adjuvant planning before surgery, yet this remains an unmet need; and when two models reach equal discrimination, the key questi...

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Literature Corpus work: 8c0d9c87-e753-5ede-8340-86e916354e7b
DOI: 10.64898/2026.08.16.26360557

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