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Integrated host–phage RNA seq analysis of Mycobacteriophage D29 infection reveals dual-arm balanced phage genome expression and inhibited expression of host transporter and VapC target genes

2025-11-22

Abstract excerpt

<h4>ABSTRACT</h4> The Mycobacteriophage D29 infects Mycobacterium species. Many of these are deadly human pathogens. In earlier studies, we performed proteomic analyses using a temperature-sensitive variant of D29, called D29ts12. This work indicated that a regulatory mechanism controls the expression of the phage’s right arm genes. In this study, we executed a transcriptomic analysis. We gained further insight i...

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Literature Corpus work
8bbb911d-8b64-5fec-97ee-1cf40b28be4b
DOI
10.1101/2025.11.21.689395
Open publication

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Integrated host–phage RNA seq analysis of Mycobacteriophage D29 infection reveals dual-arm balanced phage genome expression and inhibited expression of host transporter and VapC target genesDOI 10.1101/2025.11.21.689395
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