Novel Multifunctional NIR-II Aggregation-Induced Emission Nanoparticles Assisted Intraoperative Identification and Elimination of Residual Tumor

Abstract excerpt

<title>Abstract</title> <p>Incomplete tumor resection is the direct cause of the tumor recurrence and metastasis after surgery. Intraoperative accurate detection and elimination of microscopic residual cancer improve surgery outcomes. In this study, a powerful D1-π-A-D2-R type phototheranostic based on aggregation-induced emission (AIE)-active the second near-infrared window (NIR-II) fluorophore is designed and c...

Topics

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• Carcinoma, Non-Small-Cell Lung
• Drug Resistance, Neoplasm
• ErbB Receptors
• Fluorescence
• Fluorescent Dyes
• Lung Neoplasms
• Protein Kinase Inhibitors
• Reactive Oxygen Species

Identifiers and source

Literature Corpus work

89f41674-5b0c-589e-ac6e-6b4a54410f82

DOI

10.21203/rs.3.rs-1236043/v1