Article

Genomic analysis of cultivated infant microbiomes identifies Bifidobacterium 2’-fucosyllactose utilization can be facilitated by co-existing species

2023-04-04

Abstract excerpt

<title>Abstract</title> Human milk oligosaccharides (HMOs) ensure proper infant gut microbiome establishment. Isolate studies have revealed the genetic basis for HMO metabolism, but they exclude the possibility of HMO assimilation via synergistic interactions involving multiple organisms. Here, we investigated microbiome responses to 2'-fucosyllactose (2’FL), a prevalent HMO and infant formula additive, by est...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 89b49f71-0ee5-5d09-bac7-fad2d2089686
DOI: 10.21203/rs.3.rs-2743153/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genomic analysis of cultivated infant microbiomes identifies Bifidobacterium 2’-fucosyllactose utilization can be facilitated by co-existing speciesDOI 10.21203/rs.3.rs-2743153/v1Read

Genomic analysis of cultivated infant microbiomes identifies Bifidobacterium 2’-fucosyllactose utilization can be facilitated by co-existing speciesSemantic proximity Read

Breast milk-derived human milk oligosaccharides promote Bifidobacterium interactions within a single ecosystem.Semantic proximity Read

Infant diet promotes Bifidobacterium community cooperation within a single ecosystemSemantic proximity Read

Effects of addition of 2-fucosyllactose to infant formula on growth and specific pathways of utilization by Bifidobacterium in healthy term infantsSemantic proximity Read

Mutualistic interactions between Escherichia coli and Bifidobacterium bifidum enable degradation of human milk oligosaccharides in healthy infantsSemantic proximity Read

Identification of a novel Human Milk Oligosaccharides utilization cluster in the infant gut commensal Bacteroides doreiSemantic proximity Read

Metabolism of the predominant human milk oligosaccharide fucosyllactose by an infant gut commensalSemantic proximity Read

A bifidobacterial enzyme orchestrates ecology and function of infant gut bacterial communitySemantic proximity Read

Bifidogenic Effect of 2′-Fucosyllactose (2′-FL) on the Gut Microbiome of Healthy Formula-Fed Infants: A Randomized Clinical TrialSemantic proximity Read

Term Infant Formula Supplemented with Human Milk Oligosaccharides (2′Fucosyllactose and Lacto‐N‐ neo tetraose) Shifts Stool Microbiota and Metabolic Signatures Closer to that of Breastfed InfantsSemantic proximity Read

Milk glycan metabolism by intestinal bifidobacteria: insights from comparative genomicsSemantic proximity Read

Linking human milk oligosaccharide metabolism and early life gut microbiota: bifidobacteria and beyondSemantic proximity Read