Article

Identification of Patient Trajectories in Timeseries Clinical Transcriptomics Data

2025-12-08

Abstract excerpt

In clinical trials, it is common for only a subset of patients to respond to a given therapy. Such variability may arise from genetic differences, environmental influences, or the presence of distinct disease endotypes. Longitudinal transcriptomic profiles collected in phase 2a/2b studies provide a unique opportunity not only to investigate drug-induced biological mechanisms in humans, but also to understand why c...

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Literature Corpus work: 8932d1cb-be99-555d-bcae-11e0db320466
DOI: 10.64898/2025.12.04.692308

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