Article

AI segmentation requires accounting for brain size to maintain performance on developmental MRI cohorts

2026-07-25

Abstract excerpt

The human brain undergoes rapid developmental changes through early life, underpinning the emergence of function but also marking a period of vulnerability to a range of neurodevelopmental disorders. With dynamic changes to brain size, morphology, and imaging contrast, consistent and accurate computational neuroanatomy remains a challenge. Deep learning tools for segmentation, like SynthSeg, offer robustness to he...

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Literature Corpus work: 892de69e-66c4-5456-88e9-619534ed1675
DOI: 10.64898/2026.07.22.739983

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