Article

Korea4K: whole genome sequences of 4,157 Koreans with 107 phenotypes derived from extensive health check-ups

2022-12-26

Abstract excerpt

We present 4,157 whole-genome sequences (Korea4K) coupled with 107 health check-up parameters as the largest whole genomic resource of Koreans. Korea4K provides 45,537,252 variants and encompasses most of the common and rare variants in Koreans. We identified 1,356 new geno-phenotype associations which were not found by the previous Korea1K dataset. Phenomics analyses revealed 24 genetic correlations, 1,131 pleiot...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 887ced60-bc55-567d-a31f-e4c2f3d87f68
DOI: 10.1101/2022.12.25.521908

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Korea4K: whole genome sequences of 4,157 Koreans with 107 phenotypes derived from extensive health check-upsDOI 10.1101/2022.12.25.521908Read

Korea4K: whole genome sequences of 4,157 Koreans with 107 phenotypes derived from extensive health check-ups.Semantic proximity Read

Korean Genome Project: 1094 Korean personal genomes with clinical information.Semantic proximity Read

10,239 whole genomes with multiomic and clinical health information as the Korean Multiomics Reference datasetSemantic proximity Read

Korea10K: 10,239 whole genomes with multiomic and clinical health information as the Korean multiomics reference datasetSemantic proximity Read

Findings of a 1303 Korean whole-exome sequencing study.Semantic proximity Read

Leveraging deep phenotyping from health check-up cohort with 10,000 Korean individuals for phenome-wide association study of 136 traits.Semantic proximity Read

KRGDB: the large-scale variant database of 1722 Koreans based on whole genome sequencing.Semantic proximity Read

The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals.Semantic proximity Read

Systematic common and rare variant association testing in 392,030 whole genomes in <i>All of Us</i>Semantic proximity Read

Phenome-wide association study of a comprehensive health check-up database in a Korea population: Clinical application & trans-ethnic comparisonSemantic proximity Read

The GenomeAsia 100K Project enables genetic discoveries across Asia.Semantic proximity Read

Korean Variant Archive (KOVA): a reference database of genetic variations in the Korean population.Semantic proximity Read