Article

Exploring putative drug properties associated with TNF-alpha inhibition and identification of potential targets in cardiovascular disease using Machine Learning-Assisted QSAR Modeling and Virtual Reverse Pharmacology approach

2024-05-13

Abstract excerpt

<title>Abstract</title> <p>Introduction Cardiovascular disease is a chronic inflammatory disease with several categories of risk factors that impart a high mortality rate. Despite TNF-alpha being a prominent pro-inflammatory cytokine associated with chronic inflammation within cardiovascular disease, the adverse effects of current TNF-alpha based medications prompt an urgent need to identify efficient inhibitors...

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Literature Corpus work: 8809b4f4-fdc1-54c3-b281-bef262007fe2
DOI: 10.21203/rs.3.rs-4371326/v1

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