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Acute Changes in Cerebrospinal Fluid 5-Hydroxyindoleacetic Acid Levels Correlate with Early Clinical Exam Changes and Long-Term Motor Function in Humans with Traumatic Spinal Cord Injury

2026-08-21

Abstract excerpt

Acute traumatic spinal cord injury comprises a primary mechanical injury followed by a delayed secondary cellular injury cascade. No current monitoring modality directly detects ongoing cellular damage or its response to treatment. Essentially all spinal serotonin derives from descending raphe-spinal projections that travel alongside spinal motor and sensory pathways. Experimental spinal cord injury results in a r...

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Literature Corpus work
872fc805-4314-5a0c-b145-979ee18a8e23
DOI
10.64898/2026.08.18.26360513
Open publication

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