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Class-Wide Disproportionate Reporting of Impaired Gastric Emptying Across Nine Glucagon-Like Peptide-1 Receptor Agonist Products: A Signal-Detection Analysis of the FDA Adverse Event Reporting System

2026-07-01

Abstract excerpt

<title>Abstract</title> <p> <bold>Background.</bold> Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) delay gastric emptying as an on-target pharmacological effect. Independent pharmacovigilance analyses have reported that GLP-1 RAs account for a large share of impaired-gastric-emptying (IGE) reports in spontaneous databases (Huang et al., 2025; Tu et al., 2026). We sought to reproduce these observations a...

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Literature Corpus work: 86282cc3-1113-5a50-8df6-17ee01793577
DOI: 10.21203/rs.3.rs-9818062/v2

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