Article

In-depth behavioral characterization of a rat model of Schaaf-Yang syndrome

2025-08-05

Abstract excerpt

<title>Abstract</title> <p>Schaaf-Yang syndrome (SYS, OMIM #615547) is a rare neurodevelopmental disorder caused by truncating variants in the maternally imprinted MAGEL2 gene. It is characterized by intellectual disability, autism spectrum disorder, joint contractures, and feeding difficulties. Although MAGEL2 is deleted in most cases of Prader-Willi syndrome (PWS, OMIM #176270), SYS presents with more severe sy...

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Literature Corpus work: 8558a621-532d-5c24-b037-1a8acd77ce55
DOI: 10.21203/rs.3.rs-7068326/v1

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