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Efficacy and safety of PARP inhibitors in the treatment of BRCA-mutated breast cancer: An updated systematic review and meta-analysis of randomized controlled trials

2022-05-25

Abstract excerpt

<h4>Background: </h4> Poly-ADP-ribose polymerase inhibitors have emerged as a new class of therapeutic agents for breast cancer patients with BRCA mutations; however, the efficacy and toxicity of PARP inhibitors have not been clearly established. <h4>Methods:</h4> This study comprehensively evaluated the efficacy and safety of PARP inhibitors in BRCA mutated breast cancer patients. Online databases were systematic...

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Literature Corpus work
83cad1fc-e243-5b67-a3ad-ce651ff369e6
DOI
10.21203/rs.3.rs-1668303/v1
Open publication

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Efficacy and safety of PARP inhibitors in the treatment of BRCA-mutated breast cancer: An updated systematic review and meta-analysis of randomized controlled trialsDOI 10.21203/rs.3.rs-1668303/v1
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