Article

Synchronous B-cell precursor acute lymphoblastic leukaemia and Wilms tumour in a patient with lateralised overgrowth: causation or coincidence?

2025-10-03

Abstract excerpt

Synchronous primary malignancies are rare in paediatric patients and usually develop based on inherited cancer predisposition. We report the case of a 4-year-old girl with lateralised overgrowth who was diagnosed with concomitant B-cell precursor acute lymphoblastic leukaemia and Wilms tumour. Methylation analysis at chromosome 11p15.5 revealed a mosaic gain of methylation at IC1 on the maternal allele in kidney t...

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Literature Corpus work: 83b781be-ca10-5217-83df-1cffbbe5ebfa
DOI: 10.22541/au.175952090.09290533/v1

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