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High-resolution Microbiome Analysis Reveals Exclusionary Klebsiella Species Competition in Preterm Infants at Risk for Necrotizing Enterocolitis

2023-01-19

Abstract excerpt

Intestinal colonization with Klebsiella has been linked to necrotizing enterocolitis (NEC), but methods of analysis usually failed to discriminate Klebsiella species or strains. A novel ~2,500-base amplicon (StrainID) that spans the 16S and 23S rRNA genes was used to generate amplicon sequence variant (ASV) fingerprints for Klebsiella oxytoca and Klebsiella pneumoniae species complexes (KoSC and KpSC, respectively...

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Literature Corpus work: 8207ec0c-574c-57ad-ba77-d35a8174f3e1
DOI: 10.21203/rs.3.rs-2468771/v1

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